Ranitidine

Category: pharmacological

Aliases: Zantac

Pharmacological Mechanism

H2 receptor antagonist — historically the highest-volume PO H2 blocker. Withdrawn 2020 due to NDMA contamination across the supply chain. Less CYP DDI than cimetidine but more than famotidine.

Half-Life (t½)

PO: 3h, IV: 3h

Dosing Guidelines

• PO: Typical 150mg (Range: 75 - 300 mg)

Target Organ Systems

• digestive