Rabeprazole

Category: pharmacological

Aliases: Aciphex

Pharmacological Mechanism

Proton pump inhibitor — H+/K+-ATPase irreversible inhibitor. Less CYP2C19-dependent metabolism than omeprazole; relative DDI advantage with clopidogrel. Available OTC in some markets.

Half-Life (t½)

PO: 1h

Dosing Guidelines

• PO: Typical 20mg (Range: 20 - 60 mg)

Target Organ Systems

• digestive