Pregnenolone

Category: hormone

Pharmacological Mechanism

Master steroid precursor; allosteric NMDA modulator.

Half-Life (t½)

PO: 4h, SL: 4h

Dosing Guidelines

• PO: Typical 25 (Range: 5–100)
• SL: Typical 10 (Range: 5–50)

Target Organ Systems

• nervous

Pathways It Modulates

• Steroid hormone biosynthesis (substrate) — CYP11A1 product; root steroid precursor

Chemical Identifiers

• PubChem CID: 8955
• Formula: C21H32O2
• Molecular weight: 316.48 g/mol
• InChIKey: ORNBQBCIOKFOEO-QGVNFLHTSA-N
• SMILES: CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C

References

• PMID 24316286