Category: pharmacological
Aliases: Effient
Thienopyridine P2Y12 antagonist prodrug — hydrolyzed in intestine + activated by CYP3A4/2B6 to the active R-138727 metabolite. Faster + more consistent activation than clopidogrel; higher bleeding risk. Contraindicated in stroke/TIA history due to hemorrhagic stroke signal.
PO: 7h