Polyethylene Glycol

Category: pharmacological

Aliases: PEG, Miralax

Pharmacological Mechanism

Osmotic laxative — non-absorbed polymer pulls water into the colon by osmosis. Workhorse of chronic constipation management; safe in pregnancy. Bowel-prep formulation for colonoscopy is the same molecule at higher doses.

Half-Life (t½)

PO: 4h

Dosing Guidelines

Target Organ Systems