Pimecrolimus

Category: topical

Aliases: Elidel

Pharmacological Mechanism

Topical calcineurin inhibitor — same FKBP-12 / calcineurin pathway as tacrolimus, slightly less potent and lower systemic absorption. Approved for mild-to-moderate atopic dermatitis as a steroid alternative. Same FDA black-box (theoretical lymphoma).

Half-Life (t½)

TD: 12h

Dosing Guidelines

Target Organ Systems