Pibrentasvir

Category: pharmacological

Aliases: Component of Mavyret

Pharmacological Mechanism

Pan-genotypic HCV NS5A inhibitor — blocks viral RNA replication and assembly. Co-formulated with glecaprevir as Mavyret. >97% sustained viral response across HCV genotypes 1–6 in 8-week treatment-naive regimens.

Half-Life (t½)

PO: 23h

Dosing Guidelines

Target Organ Systems