Permethrin

Category: topical

Aliases: Elimite, Nix

Pharmacological Mechanism

Pyrethroid neurotoxin for arthropods — prolongs Na+ channel opening at insect / arachnid synapses → paralysis + death. Topical 1% for head lice, 5% for scabies. Mammalian toxicity is low (Na+ channel selectivity favors insects).

Half-Life (t½)

TD: 24h

Dosing Guidelines

Target Organ Systems