Pentoxifylline

Category: pharmacological

Aliases: Trental

Pharmacological Mechanism

Methylxanthine — increases red blood cell flexibility, decreases blood viscosity, mild antiplatelet effect. Used for intermittent claudication symptoms (modest effect) and cutaneous ulcers (off-label for vasculitis).

Half-Life (t½)

PO: 1h

Dosing Guidelines

• PO: Typical 1200mg (Range: 400 - 1200 mg)

Target Organ Systems

• integumentary
• immune-hematologic