Pantoprazole

Category: pharmacological

Aliases: Protonix

Pharmacological Mechanism

Irreversible H+/K+-ATPase inhibitor with the smallest CYP2C19 DDI footprint of the PPI class — least clopidogrel interaction. CYP2C19 substrate; metabolite further deactivated by sulfotransferase.

Half-Life (t½)

PO: 1h, IV: 1h

Dosing Guidelines

• PO: Typical 40mg (Range: 20 - 80 mg)

Target Organ Systems

• digestive