Olmesartan

Category: pharmacological

Aliases: Benicar

Pharmacological Mechanism

AT1 receptor blocker — medoxomil prodrug ester. Distinctive sprue-like enteropathy in some chronic users (rare but FDA boxed warning). Hypertension; less data in HFrEF than other ARBs.

Half-Life (t½)

PO: 13h

Dosing Guidelines

• PO: Typical 20mg (Range: 5 - 40 mg)

Target Organ Systems

• cardiovascular
• endocrine