NSI-189

Category: nootropic

Pharmacological Mechanism

Hippocampal neurogenesis stimulator — exact mechanism partially defined; raises BDNF + ERK1/2 + dentate gyrus neurogenesis in animal studies. Failed Phase 2 for major depressive disorder in 2017; biohacker interest persists.

Half-Life (t½)

PO: 17h

Dosing Guidelines

• PO: Typical 40mg (Range: 40 - 80 mg)

Target Organ Systems

• nervous