Noopept

Category: nootropic

Aliases: N-phenylacetyl-L-prolylglycine ethyl ester, GVS-111, Omberacetam

Pharmacological Mechanism

Proline-glycine dipeptide with ethyl ester. Hydrolysed to cycloprolylglycine (CPG) — proposed to be the active metabolite. CPG is an endogenous neuropeptide. Modulates AMPA + NMDA receptors; upregulates BDNF + NGF in rodent models. Russian Rx for cognitive impairment; limited Western human data.

Dosing Guidelines

Target Organ Systems