Category: pharmacological
Aliases: Component of Paxlovid
SARS-CoV-2 main protease (3CLpro / Mpro) inhibitor — blocks polyprotein cleavage. Co-administered with low-dose ritonavir as Paxlovid to inhibit nirmatrelvir's CYP3A4 metabolism. Major DDI engine via the ritonavir component during the 5-day course.
PO: 7h