Nicardipine

Category: pharmacological

Aliases: Cardene

Pharmacological Mechanism

Dihydropyridine CCB — vascular Cav1.2 selectivity. IV continuous infusion form for hypertensive emergencies + intraoperative HTN. Less reflex tachycardia than IR nifedipine.

Half-Life (t½)

PO: 3h, IV: 3h

Dosing Guidelines

• PO: Typical 30mg (Range: 20 - 120 mg)

Target Organ Systems

• cardiovascular