Nateglinide

Category: pharmacological

Aliases: Starlix

Pharmacological Mechanism

Meglitinide — same K-ATP channel closure mechanism as repaglinide, faster onset. Pre-prandial dosing for post-prandial glucose. CYP2C9 + CYP3A4 substrate.

Half-Life (t½)

PO: 1.5h

Dosing Guidelines

• PO: Typical 120mg (Range: 60 - 360 mg)

Target Organ Systems

• digestive