NADH

Category: nucleotide

Aliases: Reduced nicotinamide adenine dinucleotide

Pharmacological Mechanism

Reduced form of NAD⁺ — carries a hydride. Donates electrons to ETC Complex I driving oxidative phosphorylation. Supplemental NADH proposed to enter cells and boost ATP regeneration; evidence is preclinical-heavy with some small CFS / Parkinson's RCTs showing symptomatic improvement. Stability is poor without enteric coating.

Dosing Guidelines

• PO: Typical 10mg (Range: 5 - 20 mg)
• SL: Typical 10mg (Range: 5 - 20 mg)
• IV: Typical 10mg (Range: 5 - 20 mg)

Target Organ Systems

• nervous
• musculoskeletal

Interactions

• NAD⁺