Category: pharmacological
Aliases: CellCept, MMF
Prodrug of mycophenolic acid — selectively inhibits IMPDH2 (lymphocytes lack purine salvage and depend on de novo synthesis). Suppresses B + T cell proliferation. Backbone of transplant immunosuppression alongside calcineurin inhibitors; also lupus nephritis induction therapy.
PO: 16h, IV: 16h