Mupirocin

Category: topical

Aliases: Bactroban

Pharmacological Mechanism

Topical antibacterial — inhibits bacterial isoleucyl-tRNA synthetase. Active against staphylococci + streptococci including MRSA. Used for impetigo + nasal MRSA decolonization before surgery / dialysis catheter placement.

Half-Life (t½)

TD: 1h

Dosing Guidelines

• TD: Typical 20mg (Range: 5 - 30 mg)

Target Organ Systems

• integumentary
• immune-hematologic