Montelukast

Category: pharmacological

Aliases: Singulair

Pharmacological Mechanism

Leukotriene CysLT1 receptor antagonist — blocks LTD4 / LTE4 bronchoconstriction. Adjunctive asthma + allergic rhinitis. FDA black-box (2020) for neuropsychiatric adverse events including suicidality.

Half-Life (t½)

PO: 4h

Dosing Guidelines

• PO: Typical 10mg (Range: 4 - 10 mg)

Target Organ Systems

• respiratory
• immune-hematologic