Mixed Amphetamine Salts

Category: stimulant

Aliases: Adderall, MAS, Adderall XR

Pharmacological Mechanism

3:1 ratio of d- to l-amphetamine. L-enantiomer adds peripheral sympathomimetic activity (CV-effect contribution). XR formulation uses dual-bead profile for 10–12 h action.

Half-Life (t½)

PO: 10.4h

Dosing Guidelines

• PO: Typical 16.7mg (Range: 5 - 40 mg)

Target Organ Systems

• nervous
• cardiovascular