Misoprostol

Category: pharmacological

Aliases: Cytotec

Pharmacological Mechanism

Synthetic prostaglandin E1 analog. Multiple uses: gastric mucosal protection (NSAID-induced ulcer prevention), labor induction, postpartum hemorrhage management, medical abortion (with mifepristone), missed miscarriage management.

Half-Life (t½)

PO: 0.5h

Dosing Guidelines

• PO: Typical 200 mcg (Range: 100–800 mcg)

Target Organ Systems

• digestive

Pathways It Modulates

• Gastric acid secretion (activator) — PGE1 receptor (EP3 + EP4)

Chemical Identifiers

• PubChem CID: 5282381
• Formula: C22H38O5
• Molecular weight: 382.54 g/mol
• InChIKey: OJLOPKGSLYJEMD-URPKTTJQSA-N
• SMILES: CCCCC(C)(C/C=C/[C@H]1[C@@H](CC(=O)[C@@H]1CCCCCCC(=O)OC)O)O

References

• PMID 11821273
• PMID 15005878