Mirabegron

Category: pharmacological

Aliases: Myrbetriq

Pharmacological Mechanism

β3-adrenergic agonist — relaxes detrusor smooth muscle without anticholinergic side-effect burden. Preferred over oxybutynin / tolterodine in elderly. CYP2D6 inhibitor — caution with metoprolol, antidepressants. Modest BP elevation.

Half-Life (t½)

PO: 50h

Dosing Guidelines

• PO: Typical 50mg (Range: 25 - 50 mg)

Target Organ Systems

• cardiovascular
• digestive