Silibinin

Category: flavonoid

Aliases: Major silymarin component

Pharmacological Mechanism

Silymarin's primary active flavonolignan (~50–70% of the silymarin mix). Hepatoprotective antioxidant; IV silibinin is the antidote of choice for Amanita phalloides mushroom poisoning. Inhibits hepatic uptake of α-amanitin.

Half-Life (t½)

PO: 6h

Dosing Guidelines

Target Organ Systems