Methylprednisolone

Category: hormone

Aliases: Medrol, Solu-Medrol

Pharmacological Mechanism

Synthetic 6α-methyl glucocorticoid; ~5× cortisol potency. Used in pulse therapy for severe inflammation (auto-immune flares, transplant rejection, MS exacerbations) where rapid IV onset matters.

Half-Life (t½)

PO: 3h, IV: 3h

Dosing Guidelines

• PO: Typical 16mg (Range: 4 - 48 mg)

Target Organ Systems

• endocrine
• immune-hematologic