MDPV

Category: stimulant

Aliases: 3,4-methylenedioxypyrovalerone, bath salts

Pharmacological Mechanism

Pyrovalerone cathinone; a potent and selective DAT/NET reuptake blocker (no monoamine release, no serotonin component) — roughly an order of magnitude more potent at DAT than cocaine. Produces intense, long stimulation with strong compulsion, agitation, and "excited delirium" ("bath salts").

Dosing Guidelines

• PO: Typical 10 (Range: 5–20)
• IN: Typical 8 (Range: 3–15)

Target Organ Systems

• nervous
• cardiovascular

Notes

PubChem CID 20111961 (free base). Potent, selective catecholamine reuptake blocker (no release). DAT/NET/SERT IC50s from Baumann 2013. Plasma t½ deferred.

Chemical Identifiers

• PubChem CID: 20111961
• Formula: C16H21NO3
• Molecular weight: 275.34 g/mol
• InChIKey: SYHGEUNFJIGTRX-UHFFFAOYSA-N
• SMILES: CCCC(C(=O)C1=CC2=C(C=C1)OCO2)N3CCCC3

References

• PMID 23072836