Category: pharmacological
Aliases: Latuda, SM-13496
Second-generation antipsychotic with high-affinity D2 and 5-HT2A antagonism, 5-HT7 antagonism, 5-HT1A partial agonism, and negligible H1 / M1 / α1 activity — predicts a favourable metabolic and sedation profile relative to older atypicals. Oral bioavailability is ~2× with a ≥350 kcal meal; FDA labelling requires food co-administration.
PO: 18h