Loratadine

Category: pharmacological

Aliases: Claritin

Pharmacological Mechanism

Second-generation H1 antagonist — minimal BBB penetration → low sedation. Active descarboethoxy metabolite (desloratadine) has long half-life supporting once-daily dosing.

Half-Life (t½)

PO: 6h

Dosing Guidelines

• PO: Typical 10mg (Range: 5 - 10 mg)

Target Organ Systems

• nervous