Lidocaine

Category: pharmacological

Aliases: Xylocaine

Pharmacological Mechanism

Amide-class local anesthetic — voltage-gated Na+ channel blocker preferentially binding the inactivated state. Local infiltration, regional blocks, IV antiarrhythmic (Class IB) for ventricular arrhythmias, topical 5% patch for postherpetic neuralgia.

Half-Life (t½)

IV: 1.66h, IM: 1.66h, IN: 1.66h

Dosing Guidelines

• IV: Typical 100mg (Range: 50 - 200 mg)

Target Organ Systems

• cardiovascular