Levofloxacin

Category: pharmacological

Aliases: Levaquin

Pharmacological Mechanism

Respiratory fluoroquinolone — S-enantiomer of ofloxacin. Inhibits bacterial DNA gyrase + topoisomerase IV. Better gram-positive (S. pneumoniae) coverage than ciprofloxacin. Same fluoroquinolone class warnings: tendinopathy, neuropathy, QT prolongation, aortopathy.

Half-Life (t½)

PO: 7h, IV: 7h

Dosing Guidelines

Target Organ Systems