Lamivudine

Category: pharmacological

Aliases: 3TC, Epivir

Pharmacological Mechanism

NRTI — cytidine analog. Older HIV / HBV antiviral; lower-cost backbone in resource-limited settings. Mostly replaced in HIV ART by emtricitabine, but still used in HBV monotherapy + co-formulated dual products.

Half-Life (t½)

PO: 7h

Dosing Guidelines

• PO: Typical 300mg (Range: 100 - 300 mg)

Target Organ Systems

• immune-hematologic