L-Arginine

Category: amino-acid

Aliases: Arginine

Pharmacological Mechanism

Conditionally essential amino acid; substrate for nitric oxide synthase (NOS) → NO → vascular smooth muscle relaxation. Also urea-cycle intermediate (Krebs-Henseleit cycle in liver). Used as supplement for endothelial / cardiovascular support; effect size small at supplement doses.

Half-Life (t½)

PO: 1.32h

Dosing Guidelines

• PO: Typical 5000mg (Range: 2000 - 12000 mg)

Target Organ Systems

• cardiovascular