Ketorolac

Category: pharmacological

Aliases: Toradol, ketorolac tromethamine

Pharmacological Mechanism

Non-selective COX inhibitor; an exceptionally potent short-term analgesic given IM/IV (opioid-level acute-pain relief). Use limited to ≤5 days (all routes combined) due to GI, renal, and bleeding risk.

Half-Life (t½)

IV: 5.09h, IM: 5.09h, PO: 5.09h

Dosing Guidelines

• IV: Typical 30mg (Range: 15 - 30 mg)
• IM: Typical 30mg (Range: 15 - 60 mg)
• PO: Typical 10mg (Range: 10 - 40 mg)

Target Organ Systems

• musculoskeletal