Inositol

Category: metabolite

Aliases: myo-Inositol, Vitamin B8

Pharmacological Mechanism

Cyclic polyol — myo-inositol predominates (~95% of body inositol). Backbone of phosphatidylinositol membrane lipids and IP3 second messenger. Trialed for PCOS (insulin sensitization), anxiety, OCD; dose-dependent benefit in PCOS at 2 g BID.

Half-Life (t½)

PO: 5h

Dosing Guidelines

• PO: Typical 4000mg (Range: 1000 - 18000 mg)

Target Organ Systems

• endocrine
• reproductive