Grape Seed Extract

Category: polyphenol

Aliases: Vitis vinifera seed extract

Pharmacological Mechanism

Standardized procyanidin-rich extract. Antioxidant + endothelial vasodilator effects. Clinical evidence weakest for cardiovascular endpoints; better signal for chronic venous insufficiency + UV skin protection.

Half-Life (t½)

PO: 4h

Dosing Guidelines

• PO: Typical 200mg (Range: 100 - 600 mg)

Target Organ Systems

• cardiovascular
• integumentary