Ginkgolide A

Category: terpenoid

Pharmacological Mechanism

Cage-structure C20 diterpene lactone from Ginkgo biloba. Weak PAF (platelet-activating factor) antagonist relative to ginkgolide B. Component of standardized EGb 761 extract (24%/6% flavonoid/terpene spec).

Half-Life (t½)

PO: 4h

Dosing Guidelines

• PO: Typical 5mg (Range: 1 - 20 mg)

Target Organ Systems

• nervous
• cardiovascular