Fosinopril

Category: pharmacological

Aliases: Monopril

Pharmacological Mechanism

ACE inhibitor prodrug — phosphinic acid moiety distinguishes it. Dual hepatic + renal clearance (only ACEi with this — others are predominantly renal) → no dose adjustment in mild renal impairment.

Half-Life (t½)

PO: 12h

Dosing Guidelines

• PO: Typical 20mg (Range: 10 - 80 mg)

Target Organ Systems

• cardiovascular
• digestive
• renal