Fluvastatin

Category: pharmacological

Aliases: Lescol

Pharmacological Mechanism

First entirely synthetic statin (1994). CYP2C9 metabolism — different interaction profile than CYP3A4-metabolised statins. Lower potency than newer statins — clinical use declining.

Half-Life (t½)

PO: 1.2h

Dosing Guidelines

• PO: Typical 40mg (Range: 20 - 80 mg)

Target Organ Systems

• cardiovascular
• digestive