Category: alkaloid
Aliases: Sublimaze, Duragesic
Synthetic phenylpiperidine μ-opioid agonist; ~100× morphine potency. Lipophilic — fast onset and short duration after single dose; depot via TD patch enables 72h analgesia. Illicit fentanyl analogs drive most US opioid overdose deaths.
IV: 4h, TD: 16h, IN: 4h, SL: 4h