Famotidine

Category: pharmacological

Aliases: Pepcid

Pharmacological Mechanism

H2 receptor antagonist — suppresses gastric acid via H2 → cAMP → parietal cell. Renally cleared; no CYP metabolism → essentially no DDI footprint (preferred over cimetidine for this reason).

Half-Life (t½)

PO: 3.6h, IV: 3.6h

Dosing Guidelines

• PO: Typical 20mg (Range: 10 - 40 mg)

Target Organ Systems

• digestive