Ethosuximide

Category: pharmacological

Aliases: Zarontin

Pharmacological Mechanism

T-type Ca²⁺ channel blocker in thalamocortical circuits — first-line for absence seizures (childhood). Doesn't treat tonic-clonic; specifically fits the spike-and-wave thalamic mechanism of absence epilepsy.

Half-Life (t½)

PO: 50h

Dosing Guidelines

Target Organ Systems