Eszopiclone

Category: sleep

Aliases: Lunesta

Pharmacological Mechanism

S-enantiomer of zopiclone. GABA-A PAM with slightly less α1 selectivity than zolpidem — longer t½ → better sleep-maintenance (vs zolpidem's sleep-onset).

Half-Life (t½)

PO: 5.5h

Dosing Guidelines

• PO: Typical 1.67mg (Range: 1 - 3 mg)

Target Organ Systems

• nervous