Erythromycin (topical)

Category: topical

Pharmacological Mechanism

Topical 2% erythromycin gel/solution for inflammatory acne. Same 50S ribosomal blockade as oral erythromycin but local action minimizes systemic exposure. Bacterial resistance (Cutibacterium acnes) limits monotherapy → usually combined with benzoyl peroxide.

Half-Life (t½)

TD: 12h

Dosing Guidelines

• TD: Typical 20 mg (Range: 10–30 mg)

Target Organ Systems

• integumentary
• immune-hematologic

Chemical Identifiers

• Molecular weight: 733.93 g/mol