Emoxypine

Category: pharmacological

Aliases: Mexidol, Methylethylpyridinol

Pharmacological Mechanism

Structural analog of pyridoxine (B6). Proposed mechanisms: membrane-stabilising antioxidant, succinate-dehydrogenase activity, mild GABA-A modulation, mild benzodiazepine-site binding. Western evidence sparse; prescribed extensively in post-Soviet countries for stroke, anxiety, alcohol withdrawal, ischemia.

Half-Life (t½)

PO: 1.7h, IV: 1.7h

Dosing Guidelines

• PO: Typical 333mg (Range: 125 - 750 mg)
• IV: Typical 333mg (Range: 125 - 750 mg)
• IM: Typical 333mg (Range: 125 - 750 mg)

Target Organ Systems

• nervous