Drostanolone

Category: hormone

Aliases: Masteron, drostanolone propionate, dromostanolone

Pharmacological Mechanism

2α-methyl dihydrotestosterone derivative; a DHT-class AR agonist that cannot aromatize (no estrogenic activity) and is not further 5α-reduced. Moderately anabolic, distinctly androgenic, with mild anti-estrogenic action (historically used in breast cancer). Abused for a "hard/dry" cosmetic look; androgenic side effects (hair loss, virilization) are prominent.

Dosing Guidelines

• IM: Typical 400 (Range: 200–600)

Target Organ Systems

• endocrine
• reproductive
• musculoskeletal
• integumentary

Notes

PubChem CID 6011 (free base). Common form is drostanolone propionate (Masteron, short ester). No verbatim plasma half-life (only urinary detection-window studies) and no verbatim AR Ki in any abstract (see AUTHORING_GAPS).

Chemical Identifiers

• PubChem CID: 6011
• Formula: C20H32O2
• Molecular weight: 304.5 g/mol
• InChIKey: IKXILDNPCZPPRV-RFMGOVQKSA-N
• SMILES: C[C@@H]1C[C@]2([C@@H](CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@@H]4O)C)CC1=O)C