Dronabinol

Category: pharmacological

Aliases: Marinol

Pharmacological Mechanism

Synthetic Δ9-THC — same CB1/CB2 partial agonism. FDA-approved for chemotherapy-induced nausea + AIDS-related anorexia. Schedule III for the synthetic; CB1-mediated dysphoria + tachycardia limit dose escalation.

Half-Life (t½)

PO: 2.75h

Dosing Guidelines

• PO: Typical 5mg (Range: 2.5 - 20 mg)

Target Organ Systems

• immune-hematologic