Doxylamine

Category: sleep

Aliases: Unisom, Restavit

Pharmacological Mechanism

First-generation H1 antihistamine (ethanolamine class) with strong sedative effect. OTC sleep aid; significant anticholinergic burden — not preferred long-term in elderly.

Half-Life (t½)

PO: 10h

Dosing Guidelines

• PO: Typical 25mg (Range: 12.5 - 25 mg)

Target Organ Systems

• nervous