Doxycycline

Category: pharmacological

Aliases: Vibramycin

Pharmacological Mechanism

Tetracycline — binds bacterial 30S ribosome blocking aminoacyl-tRNA. Used for CAP atypicals, rickettsial infections, acne, malaria prophylaxis. Photosensitivity; tooth discoloration in children <8.

Half-Life (t½)

PO: 17h, IV: 17h

Dosing Guidelines

• PO: Typical 100mg (Range: 50 - 200 mg)

Target Organ Systems

• integumentary