Donepezil

Category: nootropic

Aliases: Aricept

Pharmacological Mechanism

Reversible centrally-active acetylcholinesterase inhibitor — raises CNS ACh. FDA-approved for all stages of Alzheimer's disease. Dose-dependent GI side effects (nausea, diarrhea) from peripheral cholinergic activity.

Half-Life (t½)

PO: 70h

Dosing Guidelines

• PO: Typical 10mg (Range: 5 - 23 mg)

Target Organ Systems

• nervous
• digestive