Category: peptide
Aliases: PNB-0408, N-hexanoic-Tyr-Ile-(6) aminohexanoic amide
Angiotensin IV (Ang-IV) analog developed at WSU (Harding lab). Binds hepatocyte growth factor (HGF) / c-Met signalling → synaptogenesis + spine density. Preclinically ~7 orders of magnitude more potent than BDNF on dendritic-spine outcomes. Human safety + efficacy data essentially absent.